Determination of the radiochemical purity of 99mTc- tetrofosmin: Comparison between five methods
نویسنده
چکیده
METHODS: Nineteen vials of tetrofosmin were radiolabelled with Tc and the percentages of the RCP were determined. Five different methods were compared with the standard RCP testing method (ITLC-SG, 2x20 cm): Whatman 3MM (1x10 cm) with acetone and dichloromethane (method 1); Whatman 3MM (1x10 cm) with ethyl acetate (method 2); aluminum oxide-coated plastic thin-layer chromatography (TLC) plate (1x10 cm) and ethanol (method 3); Whatman 3MM (2x20 cm) with acetone and dichloro-methane (method 4); solid-phase extraction method C18 cartridge (method 5).
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